NKorea still years away from reliable missiles


SEOUL, South Korea (AP) — After 14 years of painstaking labor, North Korea finally has a rocket that can put a satellite in orbit. But that doesn't mean Pyongyang is close to having an intercontinental ballistic missile.


Experts say North Korea is years from even having a shot at developing reliable missiles that could bombard the American mainland and other distant targets, though it did gain attention and the outrage of world leaders Wednesday with its first successful launch of a three-stage, long-range rocket.


A missile program is built on decades of systematic, intricate testing, something extremely difficult for economically struggling Pyongyang, which faces guaranteed sanctions and world disapproval each time it stages an expensive launch. North Korea will need larger and more dependable missiles, and more advanced nuclear weapons, to threaten U.S. shores, though it already poses a threat to its neighbors.


"One success indicates progress, but not victory, and there is a huge gap between being able to make a system work once and having a system that is reliable enough to be militarily useful," said Brian Weeden, a former U.S. Air Force Space Command officer and a technical adviser to the Secure World Foundation, a think tank on space policy.


North Korea's satellite launch came only after repeated failures and hundreds of millions of dollars. It is an achievement for young authoritarian leader Kim Jong Un, whose late father and predecessor, Kim Jong Il, made development of missiles and nuclear weapons a priority despite international opposition and his nation's poverty.


Kim said the achievement "further consolidated" the country's status "as a space power," the government's official Korean Central News Agency reported Thursday. It added that Kim personally issued a written launch order and "stressed the need to continue to launch satellites in the future."


South Korea's Defense Ministry said Thursday the satellite was orbiting normally at a speed of 7.6 kilometers (4.7 miles) per second, though it's not known what mission it is performing. North Korean space officials say the satellite would be used to study crops and weather patterns.


Though Pyongyang insists the project is peaceful, it also has conducted two nuclear tests and has defied international demands that it give up its nuclear weapons program.


A senior U.S. official said the satellite is tumbling in orbit and not acting as it should, but the official said that doesn't necessarily mean it is out of control. The official, who spoke on the condition of anonymity because of a lack of authorization to publicly discuss the U.S. analysis, said the important takeaway is that North Korea was able to successfully execute all three stages of the missile launch and get the satellite into space.


The U.N. Security Council said the launch violates council resolutions against the North's use of ballistic missile technology, and said it would urgently consider "an appropriate response."


"This launch is about a weapons program, not peaceful use of space," U.S. State Department spokeswoman Victoria Nuland said. Even the North's most important ally, China, expressed regret.


North Korea has long possessed the components needed to construct long-range rockets. Scientists in Pyongyang, however, had been trying and failing since 1998 to conduct a successful launch. Only this week — their fifth try — did they do so, prompting dancing in the streets of the capital.


North Korea's far more advanced rival, South Korea, has failed twice since 2009 to launch a satellite on a rocket from its own territory, and postponed two attempts in recent weeks because of technical problems.


Each advancement Pyongyang makes causes worry in Washington and among North Korea's neighbors. In 2010, U.S. Secretary of Defense Robert Gates warned that within five years the North could develop an intercontinental ballistic missile capable of reaching the United States.


But experts say the North must still surmount tough technical barriers to build the ultimate military threat: a sophisticated nuclear warhead small enough to mount on a long-range missile, something experts say will be the focus of future nuclear tests.


And despite Wednesday's launch, Pyongyang is also lacking the other key part of that equation: a reliable long-range missile.


"If in the future they develop a nuclear warhead small enough to put on a rocket, they are not going to want to put that on a missile that has a high probability of exploding on the launch pad," David Wright, a physicist with the Union of Concerned Scientists who has written extensively about North Korea's missile program, said in an email.


To create a credible missile program, experts say, North Korean technicians need to conduct many more tests that will allow them to iron out the wrinkles until they have a missile that works more often than it fails. Pyongyang's past tests have been somewhat scattershot, possibly because of the heavy international sanctions the rocket and nuclear tests have generated.


North Korea must build a larger missile than the one launched Wednesday if it wants to be able to send nuclear weapons to distant targets, analysts said.


The satellite North Korea mounted on the rocket weighs only 100 kilograms (220 pounds), according to the office of South Korean lawmaker Jung Chung-rae, who was briefed by a senior South Korean intelligence official. A nuclear warhead would be about five times heavier.


Other missing parts of the puzzle include an accurate long-range missile guidance system and a re-entry vehicle able to survive coming back into the atmosphere at the high speeds — 10,000 mph — traveled by intercontinental ballistic missiles, said Jonathan McDowell of the Harvard-Smithsonian Center for Astrophysics in Massachusetts.


Both are seen as being years off.


History also shows that first-generation, long-range missiles need dozens of test flights before they are accurate enough to be deployed.


The world's "ICBM club" has just four countries: the United States, Russia, China and France, according to Markus Schiller, an analyst with Schmucker Technologie in Germany and a leading expert on North Korean missiles.


If North Korea "really intended to become a player in the ICBM game, they would have to develop a different kind of missile, with higher performance," Schiller said. "And if they do that seriously, we would have to see flight tests every other month, over several years."


Wright said the Unha-3 rocket launched Wednesday has a potential range of 8,000 to 10,000 kilometers (4,970 to 6,210 miles), which could put Hawaii and the northwest coast of the mainland United States within range.


But even if North Korea builds a ballistic missile based on a liquid-fueled rocket like the 32-meter (105-foot)-tall Unha-3, it would take days to assemble and hours to fuel. That would make it vulnerable to attack in a pre-emptive airstrike. Solid-fueled missiles developed by the U.S. and Soviet Union are more mobile, more easily concealed and ready to launch within minutes.


Money is another problem for Pyongyang. A weak economy, chronic food shortages and the sanctions make it difficult to sustain a program that can build and operate reliable missiles.


"I don't think the young leader has any confidence that the home economy could afford a credible deterrent capability," said Zhu Feng, deputy director of the Center for International and Strategic Studies at Peking University.


Weeden said North Korea may want to create the perception that it poses a threat to the United States, but "I don't think that perception will be matched by the actual hard work and testing needed to develop and field a reliable, effective weapon system like the ICBMs deployed by the US, Russia and China."


North Korea already poses a major security threat to its East Asian neighbors. It has one of the world's largest standing armies and a formidable if aging arsenal of artillery that could target Seoul, the capital of South Korea. Nearly 30,000 U.S. forces are based in South Korea, a legacy of the 1950-53 Korean War that ended with an armistice, not a formal peace treaty.


The North's short-range rockets could also potentially target another core U.S. ally, Japan.


Daryl Kimball, executive director of the nongovernmental Arms Control Association, said those capabilities, rather than the North's future ability to strike the U.S., still warrant the most attention.


___


Pennington reported from Washington. Associated Press writers Liz Sidoti in Washington, Alexa Olesen in Beijing and Jenni Sohn in New York contributed to this report.


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Angry Birds beats Samsung in viral marketing as mobile interest surged in 2012






This past year has shown us how effective leading smartphone and mobile app companies have become at leveraging viral videos. In Ad Age’s top-10 viral videos list for 2012, Samsung (005930) and Rovio each hog two spots. The Angry Birds Space video racked up 109 million views and the Angry Birds Star Wars hit the 41 million view mark. Meanwhile, Samsung managed to get 79 million views for its Galaxy S III video and 42 million views for the LeBron’s Day clip. It’s notable that Rovio’s Angry Birds clips were far cheaper to produce, with no major stars or lavish video production gimmickry.


The smartphone/mobile app industry thus held four of the top-10 viral video slots in 2012 — the rest of the list is a motley crew of names ranging from Invisible Children and Red Bull to Intel and M&M. It is telling that the smartphone/mobile app cluster is the only industry or cultural phenomenon that generated more than one spot on the list. Popular interest in mobile content continues surging.






It might also be a sign of the times that Apple (AAPL) did not hit the top-10. Samsung’s ultra-aggressive promotional efforts have started bearing fruit. What was once a boring, stale copycat brand in 2008 has suddenly started gripping the imaginations of consumers in a completely new way.


But perhaps even more interesting is that a mobile app company with less than 100 million euros in sales in 2011 managed to beat the mighty Samsung marketing machine in 2012. Rovio is in the vanguard of spreading mobile gaming into demographic niches that have never been all that interested in technology or gaming.


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Study: People worldwide living longer, but sicker


LONDON (AP) — Nearly everywhere around the world, people are living longer and fewer children are dying. But increasingly, people are grappling with the diseases and disabilities of modern life, according to the most expansive global look so far at life expectancy and the biggest health threats.


The last comprehensive study was in 1990 and the top health problem then was the death of children under 5 — more than 10 million each year. Since then, campaigns to vaccinate kids against diseases like polio and measles have reduced the number of children dying to about 7 million.


Malnutrition was once the main health threat for children. Now, everywhere except Africa, they are much more likely to overeat than to starve.


With more children surviving, chronic illnesses and disabilities that strike later in life are taking a bigger toll, the research said. High blood pressure has become the leading health risk worldwide, followed by smoking and alcohol.


"The biggest contributor to the global health burden isn't premature (deaths), but chronic diseases, injuries, mental health conditions and all the bone and joint diseases," said one of the study leaders, Christopher Murray, director of the Institute of Health Metrics and Evaluation at the University of Washington.


In developed countries, such conditions now account for more than half of the health problems, fueled by an aging population. While life expectancy is climbing nearly everywhere, so too are the number of years people will live with things like vision or hearing loss and mental health issues like depression.


The research appears in seven papers published online Thursday by the journal Lancet. More than 480 researchers in 50 countries gathered data up to 2010 from surveys, censuses and past studies. They used statistical modeling to fill in the gaps for countries with little information. The series was mainly paid for by the Bill & Melinda Gates Foundation.


As in 1990, Japan topped the life expectancy list in 2010, with 79 for men and 86 for women. In the U.S. that year, life expectancy for men was 76 and for women, 81.


The research found wide variations in what's killing people around the world. Some of the most striking findings highlighted by the researchers: — Homicide is the No. 3 killer of men in Latin America; it ranks 20th worldwide. In the U.S., it is the 21st cause of death in men, and in Western Europe, 57th.


— While suicide ranks globally as the 21st leading killer, it is as high as the ninth top cause of death in women across Asia's "suicide belt," from India to China. Suicide ranks 14th in North America and 15th in Western Europe.


— In people aged 15-49, diabetes is a bigger killer in Africa than in Western Europe (8.8 deaths versus 1 death per 100,000).


— Central and Southeast Asia have the highest rates of fatal stroke in young adults at about 15 cases per 100,000 deaths. In North America, the rate is about 3 per 100,000.


Globally, heart disease and stroke remain the top killers. Reflecting an older population, lung cancer moved to the 5th cause of death globally, while other cancers including those of the liver, stomach and colon are also in the top 20. AIDS jumped from the 35th cause of death in 1990 to the sixth leading cause two decades later.


While chronic diseases are killing more people nearly everywhere, the overall trend is the opposite in Africa, where illnesses like AIDS, malaria and tuberculosis are still major threats. And experts warn again shifting too much of the focus away from those ailments.


"It's the nature of infectious disease epidemics that if you turn away from them, they will crop right back up," said Jennifer Cohn, a medical coordinator at Doctors Without Borders.


Still, she acknowledged the need to address the surge of other health problems across Africa. Cohn said the agency was considering ways to treat things like heart disease and diabetes. "The way we treat HIV could be a good model for chronic care," she said.


Others said more concrete information is needed before making any big changes to public health policies.


"We have to take this data with some grains of salt," said Sandy Cairncross, an epidemiologist at the London School of Hygiene and Tropical Medicine.


He said the information in some of the Lancet research was too thin and didn't fully consider all the relevant health risk factors.


"We're getting a better picture, but it's still incomplete," he said.


___


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Why Rice took her name off the list


Ambassador Susan Rice stunned Washington Thursday afternoon by withdrawing her name for consideration as secretary of State. President Obama accepted her decision.


Currently the US envoy to the United Nations, Ambassador Rice was widely seen as a top prospect to replace Secretary of State Hillary Rodham Clinton, who is retiring at the end of Mr. Obama’s first term. But her star was tarnished in September after she made erroneous statements on TV about the attack on the US consulate in Benghazi, Libya, which took the lives of four Americans, including Ambassador Christopher Stevens.


High-profile Republicans, including Sen. John McCain of Arizona, had promised a major fight if Obama had sent her name to the Senate for confirmation. By accepting her withdrawal, Obama has avoided expending political capital in trying to get her through the Senate, and also avoided refocusing the national spotlight on what went wrong in Benghazi.


RECOMMENDED: Five ways events overseas could shape Obama's second term


“If nominated, I am now convinced that the confirmation process would be lengthy, disruptive, and costly – to you and to our most pressing national and international priorities,” Rice wrote in a letter to Obama and obtained by NBC News. “That trade-off is simply not worth it to our country…. Therefore, I respectfully request that you no longer consider my candidacy at this time.”


The White House released a statement from the president indicating that he had spoken with Rice, and accepted her request to remove her name from consideration. He lauded her service as “an extraordinarily capable, patriotic, and passionate public servant.”


“While I deeply regret the unfair and misleading attacks on Susan Rice in recent weeks, her decision demonstrates the strength of her character, and an admirable commitment to rise above the politics of the moment to put our national interests first,” the president’s statement said.


At issue were her statements over what had precipitated the attack on the US mission in Benghazi. In a round of Sunday morning TV interviews five days after the Sept. 11 incident, she said it had resulted from spontaneous protests over an anti-Islamic video and was not a coordinated terrorist attack, possibly linked to Al Qaeda affiliates.


In late November, Rice acknowledged that her initial explanation was partially inaccurate, but that did not mollify her critics. She met on Capitol Hill with Senator McCain and Sens. Lindsey Graham (R) of South Carolina and Kelly Ayotte (R) of New Hampshire, but they did not back down in their opposition to her potential nomination as secretary of State.


McCain slammed the handling of Benghazi as either a coverup or incompetence. Fox News also kept up the drumbeat of pressure with in-depth coverage. The suggestion was that the Obama administration did not want to acknowledge a successful terrorist attack – one that led to the first killing of a US ambassador since 1979 – at the height of the presidential campaign.


In his statement, Obama indicated that Rice will remain as UN ambassador, and lauded her service.


“Already, she has secured international support for sanctions against Iran and North Korea, worked to protect the people of Libya, helped achieve an independent South Sudan, stood up for Israel’s security and legitimacy, and served as an advocate for UN reform and the human rights of all people,” Obama said.


“I am grateful that Susan will continue to serve as our ambassador at the United Nations and a key member of my cabinet and national security team, carrying her work forward on all of these and other issues.”


Now all eyes turn to Sen. John Kerry (D) of Massachusetts, another top prospect for secretary of State. Senator Kerry is an experienced foreign-policy hand, and has long been thought to want the job. But having him leave the Senate could cost the Democrats his seat.


Massachusetts’s other senator, Scott Brown (R), just lost reelection to Democratic firebrand Elizabeth Warren. But he remains popular in the Bay State and would be a strong candidate in a special election to replace Kerry. The Democrats don’t have an obvious choice – unless Gov. Deval Patrick (D) were to jump in.


Obama also must soon decide his nominee for another about-to-be-vacant post: secretary of Defense. News reports Thursday indicated that former US Sen. Chuck Hagel of Nebraska, a Republican, may have the edge to replace Leon Panetta, who has made clear his intention to step down.


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Official: Syria fires Scud missiles at rebels


KABUL, Afghanistan (AP) — Syrian government forces have fired Scud missiles at insurgents in recent days, escalating the 2-year-old conflict against rebels seeking to overthrow the regime, U.S. officials said Wednesday.


Speaking on condition of anonymity, two officials said forces of President Bashar Assad have fired the missiles from the Damascus area into northern Syria. These officials asked not to be named because they weren't authorized to discuss the matter publicly.


News of the missiles came on the same day that more than 100 countries, including the United States, recognized a new Syrian opposition coalition. That has further isolated Assad's regime and opened a way for greater humanitarian assistance to the forces battling to oust him.


One official said there was no indication that chemical weapons were aboard the missiles. Officials have said over the past week that they feared rebel advances were prompting Assad to consider using chemical weapons.


This official estimated that the number of Scuds fired was more than a half dozen, confirming details first reported by The New York Times.


State Department spokeswoman Victoria Nuland said Assad has fired missiles, but wouldn't specify what kind.


"As the regime becomes more and more desperate, we see it resorting to increased lethality and more vicious weapons moving forward and we have in recent days seen missiles deployed," she said.


White House press secretary Jay Carney, speaking to reporters, said he could not confirm the report, but said if true it would be a sign of desperation.


"The idea that the Syrian regime would launch missiles, within its borders, at its own people, is stunning, desperate and a completely disproportionate military escalation," Carney said.


The new development happened as officials planned an international conference to further assist opposition to Assad.


"This is the usual pattern of behavior that whenever there is an important decision that is anti-Assad taken by the international community, the Assad regime escalates the degree of violence to show its degree of displeasure," said Murhaf Jouejati, a specialist on Syrian affairs at the National Defense University. "Like saying, 'Oh, yeah? I'll show you!' "


___


Associated Press writers Julie Pace, Matthew Lee, Pauline Jelinek and Kimberly Dozier contributed to this report from Washington.


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Congress examines science behind HGH test for NFL


WASHINGTON (AP) — A congressional committee has opened a hearing to examine the science behind a human growth hormone test the NFL wants to start using on its players.


Nearly two full seasons have passed since the league and the players' union signed a labor deal that set the stage for HGH testing.


The NFL Players Association won't concede the validity of a test that's used by Olympic sports and Major League Baseball, and the sides haven't been able to agree on a scientist to help resolve that impasse.


Among the witnesses before the House Oversight and Government Reform Committee on Wednesday is Pro Football Hall of Fame member Dick Butkus. In his prepared statement, Butkus writes: "Now, let's get on with it. The HGH testing process is proven to be reliable."


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Public's response saved lives in rampage


Citizens' coolheadedness and individual preparation for coping with gunfire in public settings may have curtailed the casualty count from Tuesday's shooting at a Portland, Ore., shopping mall, law officers suggested on the day after the tragedy.


Two people died and one was critically wounded before the shooter, 22-year-old Jacob Tyler Roberts of Portland, killed himself a few minutes after running into the food court at the Clackamas Town Center mall. Officials say Mr. Roberts, wearing camouflage and a white hockey mask, had methodically fired "multiple" rounds from an assault-style rifle at random shoppers.


Most of the 10,000 Christmas shoppers at the mall appeared nearly as ready and able as police to deal with a gunman appearing suddenly in their midst, Clackamas County Sheriff Craig Roberts said on Wednesday.


"Many people have asked me why there were so few victims during this incident," said Sheriff Roberts. He listed the fact that Mr. Roberts's AR-15 semiautomatic rifle intermittently jammed and noted a well-practiced mall lockdown procedure. But he also credited "10,000 people in the mall who at one time kept a level head, got themselves out of the mall, helped others get out, secured themselves in stores.… It was really about a whole group of people coming together to make a difference."


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Law officers said during a Wednesday press conference that they did not know whether any member of the public carrying a concealed weapon had counterattacked Roberts. But they said they are certain that Roberts died by his own hand after fleeing down a stairwell from the mall's upper level.


The death rate from mass shootings has ticked up slightly in recent years, even as deaths in single-victim incidents have decreased, according to a recent analysis of FBI crime data by the Huffington Post. The worst recent mass shooting came in July in Aurora, Colo., where a gunman killed 12 people and injured 58 during a midnight screening of a new "Batman" movie.


Gun-control advocates seized on the mall shooting as a possible result of the expiration in 2004 of a national ban on assault weapons.


"Santa Claus could have been shot in the mall," said Penny Okamoto, executive director of Ceasefire Oregon, in an interview with the Portland Tribune. "If you're sick of this, you should call your legislators to tell them to fix the laws so that assault weapons don't end up in the hands of felons."


Many versions of the AR-15 were banned under the assault weapons law, but it's not known if the gun used in the Clackamas mall shooting was one of them.


Police said Roberts had no criminal record and had stolen the AR-15 from "someone he knew."


Does the collected response by shoppers at the Clackamas Town Center indicate that Americans are becoming less daunted by senseless violence and, perhaps, better ready to react? Those who back broad gun rights under the Constitution's Second Amendment suggest a shift may be under way in people's readiness to respond.


In blocking Illinois's ban on concealed weapons, the last such law in the nation, Seventh US Circuit Court of Appeals Judge Richard Posner on Tuesday implied that self-defense readiness in public is not only protected by the US Constitution, but may be good social policy. An awareness "that many law-abiding citizens are walking the streets armed may make criminals timid," he wrote in his ruling.


"As far as a social shift, I think people are getting more intelligent and appropriate in their reactions to shooters," says Dave Kopel, research director at the Independence Institute, a libertarian-leaning think tank in Golden, Colo. "Police training has changed in significant ways since the Columbine [High School] shooting [in 1999], where they no longer wait for the SWAT team to arrive but go in immediately with … the army they have. There's also an awareness [among police and the public] that if you're trying to stop a gangster from robbing a liquor store, you may have a [heck] of a fight on your hands, but that these publicity-seeking guys with mental illness, they basically crumble at first opposition."


The upshot, says Mr. Kopel: "Lying down and cowering doesn't seem to work very well, so law enforcement has gotten smarter and civilians have gotten smarter."


In Clackamas County, Sheriff Roberts said local law-enforcement personnel had trained earlier this year for a shooting scenario at Clackamas Town Center, an exercise that involved both police and retailers. On Tuesday, arriving police, in keeping with evolving police tactics nationwide, formed small teams and quickly entered the mall to pursue the shooter. Police could not say Wednesday whether any officers saw the shooter before he killed himself.


Dennis Curtis, the mall's general manager, noted that police officers told him that they were amazed "how many stores were secured and people were locked in place" upon entering the mall to look for the shooter.


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SKorea says NKorea has fired its long-range rocket


SEOUL, South Korea (AP) — North Korea fired a long-range rocket Wednesday in its second launch under its new leader, South Korean officials said, defying warnings from the U.N. and Washington only days before South Korean presidential elections.


South Korean defense officials said the rocket was fired from a west coast launch pad but there was no immediate word if the rocket was successful. North Korea had indicated technical problems with the rocket and extended its launch window. The officials spoke on condition of anonymity, citing office rules.


North Korea's Kim Jong Un took power after his father Kim Jong Il died on Dec. 17 last year, and the launch also comes about a month before President Barack Obama is inaugurated for his second term.


The North says the Unha rocket is meant to put a satellite in orbit. A similar launch in April broke apart shortly after liftoff, and the condemnation that attempt received is likely to be repeated. Washington sees the launch as a cover for a test of technology for missiles that could be used to strike the United States.


Rocket tests are seen as crucial to advancing North Korea's nuclear weapons ambitions. North Korea is thought to have only a handful of rudimentary nuclear bombs. But Pyongyang is not yet believed capable of building warheads small enough to mount on a missile that could threaten the United States.


North Korea has spent decades trying to perfect a multistage, long-range rocket. Experts say that ballistic missiles and rockets in satellite launches share similar bodies, engines and other technology. This is the fifth attempt at a long-range launch since 1998, when Pyongyang sent a rocket hurtling over Japan. Previous launches of three-stage rockets weren't considered successful.


Washington sees North Korea's pursuit of nuclear weapons and ballistic missiles as a threat to world security and to its Asian allies, Japan and South Korea.


North Korea under new leader Kim has pledged to bolster its nuclear arsenal unless Washington scraps what Pyongyang calls a hostile policy.


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DA investigating Texas' troubled $3B cancer agency


AUSTIN, Texas (AP) — Turmoil surrounding an unprecedented $3 billion cancer-fighting effort in Texas worsened Tuesday when its executive director offered his resignation and the state's chief public corruption prosecutor announced an investigation into the beleaguered agency.


No specific criminal allegations are driving the latest probe into the Cancer Prevention and Research Institute of Texas, said Gregg Cox, director of the Travis County district attorney's public integrity unit. But his influential office opened a case only weeks after the embattled agency disclosed that an $11 million grant to a private company bypassed review.


That award is the latest trouble in a tumultuous year for CPRIT, which controls the nation's second-largest pot of cancer research dollars. Amid the mounting problems, the agency announced Tuesday that Executive Director Bill Gimson had submitted his letter of resignation.


"Unfortunately, I have also been placed in a situation where I feel I can no longer be effective," Gimson wrote in a letter dated Monday.


Gimson said the troubles have resulted in "wasted efforts expended in low value activities" at the agency, instead of a focused fight against cancer. Gimson offered to stay on until January, and the agency's board must still approve his request to step down.


His departure would complete a remarkable house-cleaning at CPRIT in a span of just eight months. It began in May, when Dr. Alfred Gilman resigned as chief science officer in protest over a different grant that the Nobel laureate wanted approved by a panel of scientists. He warned it would be "the bomb that destroys CPRIT."


Gilman was followed by Chief Commercialization Officer Jerry Cobbs, whose resignation in November came after an internal audit showed Cobbs included an $11 million proposal in a funding slate without a required outside review of the project's merits. The lucrative grant was given to Dallas-based Peloton Therapeutics, a biomedical startup.


Gimson chalked up Peloton's award to an honest mistake and has said that, to his knowledge, no one associated with CPRIT stood to benefit financially from the company receiving the taxpayer funds. That hasn't satisfied some members of the agency's governing board, who called last week for more assurances that no one personally profited.


Cox said he has been following the agency's problems and his office received a number of concerned phone calls. His department in Austin is charged with prosecuting crimes related to government officials; his most famous cases include winning a conviction against former U.S. House Majority Leader Tom DeLay in 2010 on money laundering charges.


"We have to gather the facts and figure what, if any, crime occurred so that (the investigation) can be focused more," Cox said.


Gimson's resignation letter was dated the same day the Texas attorney general's office also announced its investigation of the agency. Cox said his department would work cooperatively with state investigators, but he made clear the probes would be separate.


Peloton's award marks the second time this year that a lucrative taxpayer-funded grant authorized by CPRIT instigated backlash and raised questions about oversight. The first involved the $20 million grant to M.D. Anderson Cancer Center in Houston that Gilman described as a thin proposal that should have first been scrutinized by an outside panel of scientific peer-reviewers, even though none was required under the agency's rules.


Dozens of the nation's top scientists agreed. They resigned en masse from the agency's peer-review panels along with Gilman. Some accused the agency of "hucksterism" and charting a politically-driven path that was putting commercial product-development above science.


The latest shake-up at CPRIT caught Gilman's successor off-guard. Dr. Margaret Kripke, who was introduced to reporters Tuesday, acknowledged that she wasn't even sure who she would be answering to now that Gimson was stepping down. She said that although she wasn't with the agency when her predecessor announced his resignation, she was aware of the concerns and allegations.


"I don't think people would resign frivolously, so there must be some substance to those concerns," Kripke said.


Kripke also acknowledged the challenge of restocking the peer-review panels after the agency's credibility was so publicly smeared by some of the country's top scientists. She said she took the job because she felt the agency's mission and potential was too important to lose.


Only the National Institutes of Health doles out more cancer research dollars than CPRIT, which has awarded more than $700 million so far.


Gov. Rick Perry told reporters in Houston on Tuesday that he wasn't previously aware of the resignation but said Gimson's decision to step down was his own.


Joining the mounting criticism of CPRIT is the woman credited with brainstorming the idea for the agency in the first place. Cathy Bonner, who served under former Texas Gov. Ann Richards, teamed with cancer survivor Lance Armstrong in selling Texas voters in 2007 on a constitutional amendment to create an unprecedented state-run effort to finance a war on disease.


Now Bonner says politics have sullied an agency that she said was built to fund research, not subsidize private companies.


"There appears to be a cover-up going on," Bonner said.


Peloton has declined comment about its award and has referred questions to CPRIT. The agency has said the company wasn't aware that its application was never scrutinized by an outside panel, as required under agency rules.


___


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At least 1 dead in Oregon mall shooting



At least one person is dead and several people are wounded this evening after a masked shooter opened fire at Clackamas Town Center, a mall in suburban Portland, Ore.



Police said the shooter had been "neutralized," but would not say whether the person was alive or dead.



"This is no longer an active shooter," Clackamas County Sheriff's Office spokesman Lt. James Rhodes said. "I believe the shooter has been neutralized and we are securing the mall, securing the scene and treating the wounded."



There was not an exact count of those killed or wounded, he said.



"We believe there's at least one deceased and maybe more," he said. "We know there are multiple wounded. Lifeline has landed to treat at least one of those wounded and we're set up to treat them as we find them as we search the mall."



Hundreds of people were evacuated from the busy mall full of holiday shoppers after the shooting began at around 3:30 p.m. PT.



Witnesses described seeing a gunman who looked like a teenager with a white hockey mask, wearing what was believed to be a black, bulletproof vest and carrying an assault rifle.



The person entered the mall through a Macy's store, ran through the upper level of Macy's and opened fire near the mall food court, firing multiple shots, one right after another, with what is believed to be a black, semiautomatic rifle, according to witness reports.



Witnesses described the shooter as being on a mission and determined, looking straight ahead.



Those interviewed said that Macy's shoppers and store employees huddled in a dressing room to avoid being found.



Evan Walters told ABC News Radio that he was locked in a store for his safety and he saw two people shot and heard multiple gunshots.



"It was over 20, and it was kind of surreal because we hear pops and loud noises," he said. "We're next to the food court here and we hear pops and loud noises all the time, but we don't -- nothing like that. It was very definite gunshots."


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